Melavoid™
INCI Name:
Propanediol, Water, Boerhavia Diffusa Root Extract
- Melavoid™ is a natural, lightening active ingredient that decreases skin tone evenly and uniformly, thus reducing the number of different types of hyperpigmentation spots.
- In vitro:
- shows a good affinity to bind to PPARγ and act as a natural agonist
- reduces tyrosinase enzyme formation by 63%, therefore it reduces melanogenesis
- reduces tyrosinase activity by 55%
- decreases the amount of pigment synthesized by melanocytes by 34%, without affecting their viability
- prevents an accumulation of melanin in the skin by reducing melanocyte dendrites
- In vivo:
- Decreases the intensity of skin pigmentation
- Lightens hyperpigmented areas getting a smooth and uniform complexion
- Lightening activity is higher in areas with spots than without, making it an intelligent depigmentant
- Reduces spots in number and intensity regardless of their origin (I.E. surface, UV, brown spots)